According to reader-supported reviews, this are the best OTC Allergy medicine:

Allegra Allergy 24-Hour – Best Oral Antihistamine

Allegra’s third-generation antihistamine, fexofenadine, is one of a class of medicines developed with the goal of improving clinical efficacy and minimizing side effects.

allergy medicine pollenIn a 2011 study published in the New England Journal of Medicine and the Journal of Allergy and Clinical Immunology, researchers note that fexofenadine is the most consistently non-sedating of the later antihistamines. They’re so confident it won’t cause drowsiness that they specifically recommend it for “airline pilots and others in safety-critical occupations.”

Allegra’s 24-hour formula is available in both a tablet and gel cap, making it a versatile option. If you’re someone who has trouble swallowing pills, at least you know that with Allegra, you have the option of gel caps which are much easier to take.

Children’s Allegra Allergy 12 Hour – Best for Children

Children’s Allegra contains fexofenadine, the same active ingredient found in adult Allegra. That means no risk of drowsiness. Plus there’s ample research that it’s effective against seasonal allergies and safe for kids. It can be given to children as young as two and comes in a liquid 12-hour dose.

Nasacort Allergy 24 Hour – Best Nasal Spray

Nasacort active ingredient, triamcinolone, effectively treats inflammation in the nose and, unlike competitors like Flonase, doesnt have significant adrenal suppression or the release of hormones throughout your body.  Nasacort uses a water-based formula, free of alcohol and scent; according to Dr. Cavuoto Petrizzo, this makes it less likely to cause irritation in sensitive noses.


The Best Allergy Medicine